Article

GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathway

2024-01-15

Abstract excerpt

<h4>Background: </h4> Airway remodelling plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD).Epithelial–mesenchymal transition(EMT) is a signnificant process during the occurence of airway remodelling. Increasing evidence suggests that glucose transporter 3 (GLUT3) is involved in the epithelial mesenchymal transition (EMT) process of various diseases. However, the role of GL...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e3cb7a84-d071-5177-b36a-40623b93abec
DOI: 10.21203/rs.3.rs-3849422/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathwayDOI 10.21203/rs.3.rs-3849422/v1Read

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancerSemantic proximity Read

Lyn regulates epithelial–mesenchymal transition in CS-exposed model through Smad2/3 signalingSemantic proximity Read

FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease.Semantic proximity Read

HIF-1α Contributes to the Progression of Chronic Obstructive Pulmonary DiseaseSemantic proximity Read

IGSF3 mutation identified in patient with severe COPD alters cell function and motility.Semantic proximity Read

KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse modelSemantic proximity Read

The impact of cigarette smoke exposure, and COPD or asthma status on ABC transporter gene expression in human airway epithelial cellsSemantic proximity Read

Cigarette Smoke Activates NOTCH3 to Promote Goblet Cell Differentiation in Human Airway Epithelial CellsSemantic proximity Read

Inhalation of Nicotine-containing Electronic Cigarette Vapor Exacerbates the Features of COPD in βENaC-overexpressing Mice.Semantic proximity Read

Cigarette Smoke Extract (CSE) reduces expression of functional TRPV4 channels in primary human bronchial epithelial cells differentiated at an Air Liquid Interface (ALI) in vitroSemantic proximity Read

Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.Semantic proximity Read

FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPDSemantic proximity Read