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Article

Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection

25 Jan 2016

Abstract excerpt

BACKGROUND: Human rhinoviruses (HRV) cause the majority of colds and trigger exacerbations of chronic lower airway diseases. Airway epithelial cells are the primary site for HRV infection and replication, and the initiation of host inflammatory responses. At present, the molecular mechanisms that underpin HRV responses in airway epithelial cells are incompletely understood. The aim of this study was to employ...

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PMID: 26810609
DOI: 10.1186/s12864-016-2405-z

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