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Article

Sirtuins as Key Regulators in Pancreatic Cancer: Insights into Regulatory Mechanisms and Therapeutic Implications

2024-11-14

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers, characterized by rapid progression, high resistance to conventional therapies, and a complex interplay of genetic and epigenetic alterations in key signaling pathways. Emerging evidence suggests that sirtuins modulate these key cellular processes, influencing tumor growth and progression in pancreatic cancer. This review aims to provid...

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Literature Corpus work
e3aa7829-bc65-5075-aeb0-781511804720
DOI
10.20944/preprints202411.1080.v1
Open publication

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