Article

Generation of a single-cell B cell atlas of antibody repertoires and transcriptomes to identify signatures associated with antigen-specificity

2021-11-11

Abstract excerpt

Murine models of immunization have played a major role in discovering antibody candidates against therapeutic targets. It nevertheless remains time-consuming and expensive to identify antibodies with diverse binding modalities against druggable candidate molecules. Although new genomics-based pipelines have potential to augment antibody discovery, these methods remain in their infancy due to an incomplete understa...

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Literature Corpus work: e3a59e11-f2a6-519b-ae29-acb09940bd91
DOI: 10.1101/2021.11.09.467876

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