Article

A Novel Mitophagy Enhancer Protects Cardiomyocytes against Hypoxia/Reoxygenation

2022-08-18

Abstract excerpt

Ischemia/reperfusion (I/R) injury results in cell death by inducing apoptosis. During I/R, early generation of mitochondrial reactive oxygen species (mtROS) can induce neighboring mitochondria to release additional ROS, a toxic cycle resulting in significant mitochondrial and cellular injury. Oxidative damage in the mitochondria contributes to various pathologies, including I/R injury. Accordingly, preventing mito...

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Literature Corpus work: e3a4a23b-f93c-573c-8c0a-62229755e60c
DOI: 10.20944/preprints202208.0352.v1

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