Article

Restore mitophagy is essential to prevent cardiac oxidative stress during hypertrophy

2021-01-12

Abstract excerpt

Heart failure, mostly associated with cardiac hypertrophy, is still a major cause of illness and death. Oxidative stress causes contractile failure and the accumulation of reactive oxygen species leads to mitochondrial dysfunction, associated with aging and heart failure, suggesting that mitochondria-targeted therapies could be effective in this context. The purpose of this work was to characterize how mitochondri...

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Literature Corpus work: 486bf342-7f35-5434-aea7-3889c75d2f39
DOI: 10.1101/2021.01.12.426366

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