Article

CDC20 Is Regulated by the Histone Methyltransferase, KMT5A, in Castration Resistant Prostate Cancer

2023-05-30

Abstract excerpt

The methyltransferase, KMT5A has been proposed as an oncogene in prostate cancer and therefore represents a putative therapeutic target. To confirm this hypothesis we have performed a microarray study in a prostate cancer cell line model of androgen independence following KMT5A knockdown in the presence of transcriptionally active androgen receptor (AR) to understand which genes and cellular processes are regulate...

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Literature Corpus work: e39f3f27-1eda-51ab-b724-c54280c1e553
DOI: 10.20944/preprints202305.2047.v1

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