Article

Therapeutic Targeting of Histone Lysine Demethylase KDM4B Blocks the Growth of Castration-Resistant Prostate Cancer

2021-11-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Accumulating evidence points to epigenetic mechanisms as essential in tumorigenesis. Treatment that targets epigenetic regulators is becoming an attractive strategy for cancer therapy. The role of epigenetic therapy in prostate cancer (PCa) remains elusive. Previously we demonstrated a correlation of levels of histone lysine demethylase KDM4B with the appearance...

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Literature Corpus work: 6fb2a744-54ee-5b31-b656-5886fc6bb7e8
DOI: 10.21203/rs.3.rs-957516/v2

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