Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated Analysis of Genetic Abnormalities of the Histone Lysine Methyltransferases in Prostate Cancer

7 Jan 2019

Abstract excerpt

BACKGROUND The histone methyltransferase (HMT) family includes histone lysine methyltransferases (HKMTs) and histone/protein arginine methyltransferases (PRMTs). The role of HMT gene variants in prostate cancer remains unknown. Therefore, this study aimed to evaluate HMT gene variants in the pathogenesis and prognosis of human prostate cancer, using in vitro cell studies and bioinformatics analysis. MATERIAL AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30616239
DOI: 10.12659/msm.912294

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated Analysis of Genetic Abnormalities of the Histone Lysine Methyltransferases in Prostate CancerPMID 30616239Read ↗

Deregulated expression of selected histone methylases and demethylases in prostate carcinomaSemantic proximity Read ↗

UHRF1, NSUN2, and NEIL1 were Detected as Clinical Biomarker Candidates in Prostate Adenocarcinoma with Potential Roles in Disease PathogenesisSemantic proximity Read ↗

Epigenetics-related genes in prostate cancer: expression profile in prostate cancer tissues, androgen-sensitive and -insensitive cell linesSemantic proximity Read ↗

Analysis of the role of mutations in the KMT 2D histone lysine methyltransferase in bladder cancerSemantic proximity Read ↗

Bioinformatic determination of the expression and clinical value of the histone lysine demethylase family in prostate cancerSemantic proximity Read ↗

Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancerSemantic proximity Read ↗

Multiple Highly Methylated CpG Sites as Potential Epigenetic Markers for the Diagnosis of Prostate CancerSemantic proximity Read ↗

Epigenetic Changes in Prostate Cancer: Implication for Diagnosis and TreatmentSemantic proximity Read ↗

SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3.Semantic proximity Read ↗

Genome-Wide Methylation Analysis of Prostate Tissues Reveals Global Methylation Patterns of Prostate CancerSemantic proximity Read ↗

Epigenetic insights into prostate cancer: exploring histone modifications and their therapeutic implicationsSemantic proximity Read ↗

Comprehensive analysis of m7G-related Genes METTL1 and WDR4 for predicting prognosis and oncogenic functions in prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.