Article

Human genomics of acute liver failure due to hepatitis B virus infection: an exome sequencing study in liver transplant recipients

2018-05-11

Abstract excerpt

Acute liver failure (ALF) or fulminant hepatitis is a rare, yet severe outcome of infection with hepatitis B virus (HBV) that carries a high mortality rate. The occurrence of a life-threatening condition upon infection with a prevalent virus in individuals without known risk factors is suggestive of pathogen-specific immune dysregulation. In the absence of established differences in HBV virulence, we hypothesized...

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Literature Corpus work: e363fb1c-f900-59ea-9ea9-5721192466ec
DOI: 10.1101/320374

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