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Article

The impact of complement factor H-related protein gene deletions on kidney transplantation

2024-02-19

Abstract excerpt

<h4>ABSTRACT</h4> We recently reported that a homozygous deletion in the complement factor H-related ( CFHR) locus predisposed kidney transplant patients to rejection. As donors carried intact genes, the susceptibility may have resulted from alloimmune reaction to FHR proteins. However, we found no evidence for anti-FH response. It is therefore possible that CFHR deletions as such affect the rejection risk. Her...

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Literature Corpus work
e362f48a-f4ab-5361-a565-cdd0d939f8f1
DOI
10.1101/2024.02.18.24301068
Open publication

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