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Article

Epigenetic modifications in muscle regeneration and progression of Duchenne muscular dystrophy.

Clinical epigenetics - 19 Jan 2021

Rugowska Anna, Starosta Alicja, Konieczny Patryk

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a multisystemic disorder that affects 1:5000 boys. The severity of the phenotype varies dependent on the mutation site in the DMD gene and the resultant dystrophin expression profile. In skeletal muscle, dystrophin loss is associated with the disintegration of myofibers and their ineffective regeneration due to defective expansion and differentiation of the muscle stem cell...

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Share to Disease Progression
Share to DNA Methylation
Share to Dystrophin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Genetic Therapy

Share to Muscle, Skeletal

Share to Muscular Dystrophy, Duchenne

Share to Regeneration

Source

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Identifiers

PMID: 33468200
DOI: 10.1186/s13148-021-01001-z
PMCID: PMC7814631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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