Article

Dysregulation of circular RNAs in myotonic dystrophy type 1

2018-10-24

Abstract excerpt

Circular RNAs (circRNAs) constitute a recently re-discovered class of non-coding RNAs functioning as sponge for miRNAs and proteins, affecting RNA splicing and regulating transcription. CircRNAs are generated by “back-splicing”, linking covalently 3’- and 5’-ends of exons. Thus, circRNA levels might be deregulated in conditions associated to altered RNA-splicing. Indeed, increasing evidence indicates their role in...

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Literature Corpus work: ea84dc86-c174-529d-9a51-6169476804fa
DOI: 10.1101/452391

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