Article

Genetic variation in HLA, IGKV and HHEX loci influence mRNA vaccine-induced long-lasting humoral protection against COVID-19

2025-10-23

Abstract excerpt

There is a notable variability in the humoral response mounted across individuals after COVID-19 vaccination. A growing number of studies link genetic factors to antigen-specific antibody levels after the first two immunizations. However, knowledge on the potential influence of genetics on the neutralizing activity of vaccine-induced antibodies and the humoral immune response to the third immunization is limited....

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Literature Corpus work: e2ab61c1-b7e0-50df-804c-ad9de7ccf3cc
DOI: 10.1101/2025.10.21.25337971

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