Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.

doi:10.1097/JTO.0b013e3182295917

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Nov 2011

Micke Patrick, Edlund Karolina, Holmberg Lars, Kultima Hanna Göransson, Mansouri Larry, Ekman Simon, Bergqvist Michael, Scheibenflug Lena, Lamberg Kristina, Myrdal Gunnar, Berglund Anders, Andersson Annsofie, Lambe Mats, Nyberg Fredrik, Thomas Andrew, Isaksson Anders, Botling Johan

Abstract excerpt

INTRODUCTION: Non-small cell lung cancer (NSCLC) is characterized by a multitude of genetic aberrations with unknown clinical impact. In this study, we aimed to identify gene copy number changes that correlate with clinical outcome in NSCLC. To maximize the chance to identify clinically relevant events, we applied a strategy involving two prognostically extreme patient groups. METHODS: Short-term (<20 month; n =...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Large Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Chromosomes, Human

Share to Gene Dosage

Share to Microarray Analysis

Share to Real-Time Polymerase Chain Reaction

Share to Survival Rate

Share to Survivors

Source

Open in PubMed

Identifiers

PMID: 22011649
DOI: 10.1097/JTO.0b013e3182295917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.PMID 22011649Read ↗

Whole Genome Copy Number Analyses Reveal a Highly Aberrant Genome in TP53 Mutant Lung Adenocarcinoma TumorsSemantic proximity Read ↗

Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors.Semantic proximity Read ↗

Landscape of somatic allelic imbalances and copy number alterations in human lung carcinomaSemantic proximity Read ↗

Characterizing the cancer genome in lung adenocarcinoma.Semantic proximity Read ↗

Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.Semantic proximity Read ↗

Genome-Wide Screening of Genomic Alterations and Their Clinicopathologic Implications in Non–Small Cell Lung CancersSemantic proximity Read ↗

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability.Semantic proximity Read ↗

Genomic Profiles in Stage I Primary Non Small Cell Lung Cancer Using Comparative Genomic Hybridization Analysis of cDNA MicroarraysSemantic proximity Read ↗

Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features.Semantic proximity Read ↗

Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential TargetSemantic proximity Read ↗

MYC amplification as a prognostic marker of early-stage lung adenocarcinoma identified by whole genome copy number analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.