Article

Uncovering the hidden structure of dynamic T cell composition in peripheral blood during cancer immunotherapy: a topic modeling approach

2023-04-28

Abstract excerpt

Immune checkpoint inhibitors (ICIs), now mainstays in the treatment of cancer treatment, show great potential but only benefit a subset of patients. A more complete understanding of the immunological mechanisms and pharmacodynamics of ICI in cancer patients will help identify the patients most likely to benefit and will generate knowledge for the development of next-generation ICI regimens. We set out to interroga...

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Literature Corpus work: e269e8fd-8d05-5757-bc2e-c2cca21cb8e8
DOI: 10.1101/2023.04.24.538095

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