Article

Parallel Evolution in the Emergence of Highly Pathogenic Avian Influenza A Viruses

2018-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Parallel molecular evolution and adaptation are important phenomena commonly observed in viruses. Here we exploit parallel molecular evolution to understand virulence evolution in avian influenza viruses (AIV). Highly-pathogenic AIVs independently evolve from low-pathogenic ancestors via acquisition of a polybasic cleavage sites (pCS). Why some AIV lineages but not others evolve in this way is u...

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Literature Corpus work: e232da8c-0112-5f19-aa60-1b8fef569091
DOI: 10.1101/370015

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