Article

Disrupting central carbon metabolism increases antibiotic susceptibility in <i>Vibrio cholerae</i>

2022-12-23

Abstract excerpt

Antibiotic tolerance, the ability of bacteria to sustain viability in the presence of typically bactericidal antibiotics for extended time periods, is an understudied contributor to treatment failure. The Gram-negative pathogen Vibrio cholerae , the causative agent of cholera disease, becomes highly tolerant to β-lactam antibiotics (penicillin and related compounds) in a process requiring the two-component system...

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Literature Corpus work: e21694fa-6ad2-511b-a41b-423b354d8970
DOI: 10.1101/2022.12.22.521713

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