Article

Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis

2024-11-17

Abstract excerpt

Antibiotic tolerance, the widespread ability of diverse pathogenic bacteria to sustain viability in the presence of typically bactericidal antibiotics for extended time periods, is an understudied steppingstone towards antibiotic resistance. The Gram-negative pathogen Vibrio cholerae , the causative agent of cholera, is highly tolerant to β-lactam antibiotics. We previously found that the disruption of glycolysis...

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Literature Corpus work: c3e34095-d714-5781-916a-9a351d195383
DOI: 10.1101/2024.11.13.623475

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