Back to search

Article

Phenotypic and multi-omics characterization of <i>Escherichia coli</i> K-12 adapted to quaternary ammonium compounds identifies lipid A and cell envelope alterations regulated by mar-sox-rob and stress inducible pathways

2020-07-14

Abstract excerpt

Quaternary ammonium compounds (QACs) benzalkonium (BZK) and cetrimide (CET) are common disinfectants used to inhibit or eradicate Gram-negative bacteria in clinical and agricultural products. QAC tolerance in Escherichia coli and other Enterobacterales species can confer cross-resistance to various clinically used antibiotics, making it important to understand mechanisms of QAC tolerance in greater depth. QAC ada...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8c944502-0865-5138-8d89-eff8a2c0cf15
DOI
10.1101/2020.07.13.201814
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Phenotypic and multi-omics characterization of <i>Escherichia coli</i> K-12 adapted to quaternary ammonium compounds identifies lipid A and cell envelope alterations regulated by mar-sox-rob and stress inducible pathwaysDOI 10.1101/2020.07.13.201814
High-level carbapenem tolerance requires antibiotic-induced outer membrane modificationsSemantic proximity
The <i>Acinetobacter baumannii</i> virulence factor Omp33 is important for tolerance to benzalkonium chlorideSemantic proximity
Aminoglycoside heteroresistance in <i>Enterobacter cloacae</i> is driven by the cell envelope stress responseSemantic proximity
Genome-wide screening of the Keio collection identifies genetic determinants of Escherichia coli sensitivity and tolerance to benzoic acid.Semantic proximity
Peptidoglycan recycling contributes to outer membrane integrity and carbapenem tolerance in <i>Acinetobacter baumannii</i>Semantic proximity
Accessory genes define species-specific pathways to antibiotic resistanceSemantic proximity
Genomic Pipeline for Analysis of Mutational Events in Bacteria.Semantic proximity
Mutational Activation of Antibiotic-Resistant Mechanisms in the Absence of Major Drug Efflux Systems of Escherichia coli.Semantic proximity
Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of <i>Klebsiella pneumoniae</i>Semantic proximity
Multi-omics profiling of cross-resistance between ceftazidime-avibactam and meropenem identifies common and strain-specific mechanisms in <i>Pseudomonas aeruginosa</i> clinical isolatesSemantic proximity
Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals.Semantic proximity
Comprehensive proteomic and metabolomic profiling of <i>mcr-1</i> mediated colistin resistance in <i>Escherichia coli</i>Semantic proximity
Select a neighboring publication to make it the new centre.