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Cell specific peripheral immune responses predict survival in critical COVID-19 patients

15 Feb 2022

Abstract excerpt

SARS-CoV-2 triggers a complex systemic immune response in circulating blood mononuclear cells. The relationship between immune cell activation of the peripheral compartment and survival in critical COVID-19 remains to be established. Here we use single-cell RNA sequencing and Cellular Indexing of Transcriptomes and Epitomes by sequence mapping to elucidate cell type specific transcriptional signatures that...

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PMID: 35169146
DOI: 10.1038/s41467-022-28505-3

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