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Specialized interferon action in COVID-19

25 Feb 2022

Abstract excerpt

The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both protective and harmful effects being documented. We report here a multiomics investigation of systemic IFN signaling in hospitalized COVID-19 patients, defining the multiomics biosignatures associated with varying levels of 12 different type I, II, and III IFNs. The antiviral transcriptional response in circulating immune...

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COVID-19 Clinical Research Studies
Inflammasome and immune disorders
Long-Term Effects of COVID-19

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35217532
DOI: 10.1073/pnas.2116730119

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