Article

Amniotic membrane-derived stromal cells release extracellular vesicles that favor regeneration of dystrophic skeletal muscles

2023-01-23

Abstract excerpt

<title>Abstract</title> <bold>Background</bold> Duchenne muscular dystrophy (DMD) is a muscle disease caused by mutations in the dystrophin gene characterized by myofiber fragility and progressive muscle degeneration. The genetic defect results in a reduced number of self-renewing satellite cells (MuSCs) and an impairment of their activation and differentiation which lead to the exhaustion of skeletal muscle r...

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Literature Corpus work: 590db361-90a6-5df3-8ac9-1cdfe95023c2
DOI: 10.21203/rs.3.rs-2103547/v1

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