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Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling

26 Sept 2022

Abstract excerpt

Muscle satellite stem cells (MuSCs) are responsible for skeletal muscle growth and regeneration. Despite their differentiation potential, human MuSCs have limited in vitro expansion and in vivo migration capacity, limiting their use in cell therapies for diseases affecting multiple skeletal muscles. Several protocols have been developed to derive MuSC‐like progenitors from human induced pluripotent stem (iPS)...

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PMID: 36161772
DOI: 10.15252/emmm.202114526

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