Article

Lipid-mediated insertion of Toll-like receptor (TLR) ligands for facile immune cell engineering

2019-11-16

Abstract excerpt

Cell-based immunotherapies have tremendous potential to treat many diseases, such as activating immunity in cancer or suppressing it in autoimmune diseases. Most cell-based cancer immunotherapies in the clinic provide adjuvant signals through genetic engineering to enhance T cell functions. However, genetically encoded signals have minimal control over dosing and persist for the life of a cell lineage. These prope...

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Literature Corpus work: e1e62145-6277-540e-ae8c-263ae3a18810
DOI: 10.1101/840876

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