Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure, function, property, and role in neurologic diseases and other diseases of the sHsp22.

Journal of neuroscience research - 1 Aug 2007

Hu Zhiping, Chen Lan, Zhang Jie, Li Ting, Tang Jianguang, Xu Niangui, Wang Xiang

Abstract excerpt

Small heat shock proteins are members of the heat shock proteins family. They share important identical features: 1) they form the conserved structure 'alpha-crystallin domain' with about 80-100 residues in the C-terminal part of the proteins; 2) they have monomeric molecular masses ranging in 12-43 kDa; 3) they associate into large oligomers consisting in many cases of subunits; 4) they increase expression under...

Topics

Animals
Brain Ischemia
Heat-Shock Proteins
Humans
Molecular Chaperones
Molecular Structure
Mutation
Myocardial Ischemia
Neoplasms
Nervous System Diseases
Protein Serine-Threonine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reperfusion Injury

Structure-Activity Relationship

Source

Identifiers

PMID: 17304582
DOI: 10.1002/jnr.21231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure, function, property, and role in neurologic diseases and other diseases of the sHsp22.PMID 17304582Read ↗

Insights on Human Small Heat Shock Proteins and Their Alterations in DiseasesSemantic proximity Read ↗

Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunitiesSemantic proximity Read ↗

Small heat shock proteins and protein-misfolding diseases.Semantic proximity Read ↗

The family of mammalian small heat shock proteins (HSPBs): implications in protein deposit diseases and motor neuropathies.Semantic proximity Read ↗

Novel insights in the disease biology of mutant small heat shock proteins in neuromuscular diseases.Semantic proximity Read ↗

The small heat shock protein Hsp27: Present understanding and future prospects.Semantic proximity Read ↗

Mutations of small heat shock proteins and human congenital diseases.Semantic proximity Read ↗

Small heat shock proteins in neurodegenerative diseases.Semantic proximity Read ↗

Study of HSPB6: Insights into the Properties of the Multifunctional Protective AgentSemantic proximity Read ↗

[Molecular mechanisms of small heat shock protein-related disease and its therapeutic strategies].Semantic proximity Read ↗

The small heat shock proteins family: the long forgotten chaperones.Semantic proximity Read ↗

Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.