Article
Role of the HSP70 Co-Chaperone SIL1 in Health and Disease.
International journal of molecular sciences - 4 Feb 2021
Ichhaporia Viraj P, Hendershot Linda M
Abstract excerpt
Cell surface and secreted proteins provide essential functions for multicellular life. They enter the endoplasmic reticulum (ER) lumen co-translationally, where they mature and fold into their complex three-dimensional structures. The ER is populated with a host of molecular chaperones, associated co-factors, and enzymes that assist and stabilize folded states. Together, they ensure that nascent proteins mature...
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