Article

With or Without You: Co-chaperones Mediate Health and Disease by Modifying Chaperone Function and Protein Triage

2021-10-11

Abstract excerpt

Heat shock proteins (HSPs) are a family of molecular chaperones that regulate essential protein refolding and triage decisions to maintaining protein homeostasis. Numerous co-chaperone proteins directly interact and modify the function of HSPs, and these interactions impact the outcome of protein triage, impacting everything from structural proteins to cell signaling mediators. The chaperone/co-chaperone machinery...

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Literature Corpus work: 6b39e6d2-1638-5f2f-bba6-4713519546c3
DOI: 10.20944/preprints202110.0168.v1

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