Article

The Endoplasmic Reticulum Membrane Complex Promotes Proteostasis of GABA <sub>A</sub> Receptors

2022-03-04

Abstract excerpt

<h4>ABSTRACT</h4> The endoplasmic reticulum membrane complex (EMC) plays a critical role in the biogenesis of tail-anchored and a subset of multi-pass membrane proteins in the endoplasmic reticulum. However, due to the nearly exclusive expression of neurotransmitter-gated ion channels in the central nervous system, the role of the EMC in their biogenesis is not well understood. In this study, we demonstrated that...

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Literature Corpus work: 7e57b710-82f9-5d71-a66a-c834d80a5c42
DOI: 10.1101/2022.03.03.482920

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