Article

Developing hippocampal spheroids model ictogenesis and epileptogenesis

2023-01-08

Abstract excerpt

Three-dimensional (3D) neural cell cultures inherently lend themselves to high-throughput network electrophysiology studies addressing brain function in health and disease in a more realistic architectural complexity than two-dimensional neural networks. Epilepsy is the emblem of brain network disorders, as it reflects aberrant circuit reorganization and hyper-synchronization, resulting in sudden and uncontrolled...

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Literature Corpus work: e1cfbe78-2cc5-5983-af4c-3af20d1f004d
DOI: 10.1101/2023.01.06.523024

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