Article

The intrinsic clock of the hippocampal subfield CA3 rescues limbic seizures in a biohybrid graft-host interaction in vitro

2023-01-27

Abstract excerpt

<h4>ABSTRACT</h4> Hippocampal dysfunction is the hallmark of mesial temporal lobe epilepsy (MTLE), the most common epileptic syndrome in adults and the most often refractory to medical therapy. Deep brain stimulation (DBS) may ameliorate drug-refractory MTLE, but it still cannot guarantee a seizure-free life. One major drawback is that the stimulation policy is informed by trial-and-error rather than by the opera...

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Identifiers and source

Literature Corpus work: 12977506-80be-5958-aa33-b676736eb621
DOI: 10.1101/2023.01.26.525630

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