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Integrative multi-omics analysis reveals molecular landscape associated with chronic lipid accumulation following contusive spinal cord injury

2023-01-04

Abstract excerpt

Lipid metabolism is a critical process that occurs in the lipid-rich spinal cord during damage and repair. Here, we integrated ultrastructural characteristics with multi-omics analysis as well as transcriptomic, untargeted, targeted proteomic, lipidomic, and N6-methyladenosine (m 6 A) epitranscriptomic profiling in a clinically relevant spinal cord injury (SCI) model. We observed lipid accumulation, lysosome-based...

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Literature Corpus work
64a8665a-c2e5-52f8-bc61-5e40d46a6330
DOI
10.21203/rs.3.rs-2437316/v1
Open publication

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Integrative multi-omics analysis reveals molecular landscape associated with chronic lipid accumulation following contusive spinal cord injuryDOI 10.21203/rs.3.rs-2437316/v1
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