Article
Emerging role of lipid metabolism alterations in Cancer stem cells.
Journal of experimental & clinical cancer research : CR - 15 Jun 2018
Yi Mei, Li Junjun, Chen Shengnan, Cai Jing, Ban Yuanyuan, Peng Qian, Zhou Ying, Zeng Zhaoyang, Peng Shuping, Li Xiaoling, Xiong Wei, Li Guiyuan, Xiang Bo
Abstract excerpt
BACKGROUND: Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the bulk of tumor cells, CSCs or TICs are refractory to traditional therapy and are responsible for relapse or disease recurrence in cancer patients. Stem cells have distinct metabolic properties compared to differentiated cells, and metabolic...
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