Article

DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

2021-09-23

Abstract excerpt

<h4>Background: </h4> Inflammatory Bowel Disease (IBD) is established to drive pathological sequelae in organ systems outside the intestine, including the central nervous system (CNS). Many patients exhibit cognitive deficits, particularly during disease flare. The connection between colonic inflammation and neuroinflammation remains unclear and characterization of the neuroinflammatory phenotype in the brain duri...

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Literature Corpus work: e1863c23-2978-517d-aec8-a5dd1c280fd7
DOI: 10.1101/2021.09.22.461244

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DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimodDOI 10.1101/2021.09.22.461244Read

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