Article

A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis

2023-08-13

Abstract excerpt

The gut and brain are increasingly linked in human disease, with neuropsychiatric conditions classically attributed to the brain showing an involvement of the intestine and inflammatory bowel diseases (IBDs) displaying an ever-expanding list of neurological comorbidities. To identify molecular systems that underpin this gut-brain connection and thus discover therapeutic targets, experimental models of gut dysfunct...

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Literature Corpus work: d8c2500f-7724-5cb1-a1fa-7e0f62346ae9
DOI: 10.1101/2023.08.10.552488

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