Article

DSS Colitis Model: Traps, Tricks, and Reporting Recommendations

2026-03-16

Abstract excerpt

The dextran sulfate sodium (DSS) colitis model is the most widely used experimental model of inflammatory bowel disease (IBD) due to its simplicity and versatility, with over 7,000 PubMed entries in the last decade and an exponential rise in recent years. Since its initial description in 1985, DSS colitis has been extensively evaluated across species, most notably in mice and rats, and has yielded substantial insi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 316264e8-857d-5add-83a0-f68f692da8cc
DOI: 10.20944/preprints202603.1112.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DSS Colitis Model: Traps, Tricks, and Reporting RecommendationsDOI 10.20944/preprints202603.1112.v1Read

Inflammatory bowel disease, past, present and future: lessons from animal models.Semantic proximity Read

[Ulcerative colitis].Semantic proximity Read

Harnessing murine models of Crohn's disease ileitis to advance concepts of pathophysiology and treatment.Semantic proximity Read

Differential colitis susceptibility of Th1- and Th2-biased mice: A multi-omics approachSemantic proximity Read

Integrated multi-model analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBDSemantic proximity Read

Dynamic Monitoring of Cross-Bred Dogs for Translational Research in Ulcerative ColitisSemantic proximity Read

The Gut-<em>Ex-vivo</em> System (GEVS) Is a Dynamic and Versatile Tool for the Study of Dnbs-Induced IBDin BALB/c and C57BL/6 MiceSemantic proximity Read

Deciphering the different phases of preclinical inflammatory bowel disease.Semantic proximity Read

Current overview of extrinsic and intrinsic factors in etiology and progression of inflammatory bowel diseases.Semantic proximity Read

A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitisSemantic proximity Read

[Inflammatory bowel disease: pathogenesis and therapy].Semantic proximity Read

Cold stress induces colitis-like phenotypes in mice by altering gut microbiota and metabolitesSemantic proximity Read