Article

Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivation

2025-08-12

Abstract excerpt

Antimicrobial Resistance (AMR) is a major threat to public health. Plasmids are mobile genetic elements that can rapidly spread across bacterial populations, promoting the dissemination of AMR genes in clinical bacteria. In addition, plasmids are enriched in insertion sequences (IS), which are small transposable elements able to translocate between genetic locations. Importantly, IS transpositions commonly lead to...

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Literature Corpus work: 7b71e0c6-5887-5b72-a0f2-82f32e33c7dd
DOI: 10.1101/2025.08.12.669853

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