Article

Evolutionary mechanisms that determine which bacterial genes are carried on plasmids

2020-08-04

Abstract excerpt

The evolutionary pressures that determine the location (chromosomal or plasmid-borne) of bacterial genes are not fully understood. We investigate these pressures through mathematical modelling in the context of antibiotic resistance, which is often found on plasmids. Our central finding is that gene location is under positive frequency-dependent selection: the higher the frequency of one form of resistance compare...

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Literature Corpus work: d51ee814-a757-54c4-a93d-6000fc3a877a
DOI: 10.1101/2020.08.04.236455

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