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Article

Emerging patterns of plasmid-host coevolution that stabilize antibiotic resistance.

Scientific reports - 7 Jul 2017

Stalder Thibault, Rogers Linda M, Renfrow Chris, Yano Hirokazu, Smith Zachary, Top Eva M

Abstract excerpt

Multidrug resistant bacterial pathogens have become a serious global human health threat, and conjugative plasmids are important drivers of the rapid spread of resistance to last-resort antibiotics. Whereas antibiotics have been shown to select for adaptation of resistance plasmids to their new bacterial hosts, or vice versa, a general evolutionary mechanism has not yet emerged. Here we conducted an experimental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28687759
DOI: 10.1038/s41598-017-04662-0
PMCID: PMC5501780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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