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Article

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities.

Nature communications - 11 May 2021

Alonso-Del Valle Aida, León-Sampedro Ricardo, Rodríguez-Beltrán Jerónimo, DelaFuente Javier, Hernández-García Marta, Ruiz-Garbajosa Patricia, Cantón Rafael, Peña-Miller Rafael, San Millán Alvaro

Abstract excerpt

Plasmid persistence in bacterial populations is strongly influenced by the fitness effects associated with plasmid carriage. However, plasmid fitness effects in wild-type bacterial hosts remain largely unexplored. In this study, we determined the fitness effects of the major antibiotic resistance plasmid pOXA-48_K8 in wild-type, ecologically compatible enterobacterial isolates from the human gut microbiota. Our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33976161
DOI: 10.1038/s41467-021-22849-y
PMCID: PMC8113577

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