Article

Can cancer GWAS variants modulate immune cells in the tumor microenvironment?

2018-12-13

Abstract excerpt

Genome-wide association studies (GWAS) have hitherto identified several genetic variants associated with cancer susceptibility, but the molecular functions of these risk modulators remain largely uncharacterized. Recent studies have begun to uncover the regulatory potential of non-coding GWAS SNPs by using epigenetic information in corresponding cancer cell types and matched normal tissues. However, this approach...

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Literature Corpus work: e13574c5-04c5-5e49-8a82-4240d99a1a1d
DOI: 10.1101/493171

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