Article

Mitochondrial Apurinic/Apyrimidinic Endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

2020-08-07

Abstract excerpt

<title>Abstract</title> <p>Background: Hepatocellular carcinoma (HCC) is the leading cause of primary liver cancers. Surveillance of individuals at specific risk of developing HCC, early diagnostic markers, and new therapeutic approaches are essential to obtain a reduction in disease-related mortality. Apurinic/apyrimidinic endonuclease 1 (APE1) expression levels and its cytoplasmic localization have been reporte...

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Literature Corpus work: e12bd87d-6cd7-5270-9b77-7e9bc17b7a9b
DOI: 10.21203/rs.3.rs-23299/v3

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