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EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients

17 Oct 2018

Abstract excerpt

The roles of exonuclease 1 (EXO1) in hepatocellular carcinoma (HCC) tumorigenesis and progression remain unclear. This study aimed to assess the prognostic value and therapeutic potential of EXO1 in HCC. Exo1 gene copy numbers were obtained from three Oncomine microarray datasets (n = 447). EXO1 mRNA expression was validated by semi-quantitative PCR and QuantiGene® 2.0 assays. Cell growth curve and colony...

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Cancer Genomics and Diagnostics
DNA Repair Mechanisms
Genetic factors in colorectal cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30328366
DOI: 10.1080/15384101.2018.1534511

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