Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers.

British journal of cancer - 16 Feb 2010

Al-Attar A, Gossage L, Fareed K R, Shehata M, Mohammed M, Zaitoun A M, Soomro I, Lobo D N, Abbotts R, Chan S, Madhusudan S

Abstract excerpt

BACKGROUND: Altered DNA repair may be associated with aggressive tumour biology and impact upon response to chemotherapy and radiotherapy. We investigated whether expression of human AP endonuclease (APE1), a key multifunctional protein involved in DNA BER, would impact on clinicopathological out...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biliary Tract Neoplasms
Share to Carcinoma
Share to DNA-(Apurinic or Apyrimidinic Site) Lyase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Ovarian Neoplasms

Share to Pancreatic Neoplasms

Share to Stomach Neoplasms

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 20087352
DOI: 10.1038/sj.bjc.6605541
PMCID: PMC2837561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20087352-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers.PMID 20087352Read ↗

Clinicopathological significance of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in oestrogen-receptor-positive breast cancerSemantic proximity Read ↗

APE1 overexpression promotes the progression of ovarian cancer and serves as a potential therapeutic targetSemantic proximity Read ↗

Clinical Significance of Apurinic/Apyrimidinic Endodeoxyribonuclease 1 and MicroRNA Axis in Hepatocellular CarcinomaSemantic proximity Read ↗

Targeting APE1 endonuclease activity impairs metastasis and enhances genotoxic therapy response in pancreatic cancerSemantic proximity Read ↗

Mitochondrial Apurinic/Apyrimidinic Endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinomaSemantic proximity Read ↗

APE1 and SSRP1 is overexpressed in muscle invasive bladder cancer and associated with poor survivalSemantic proximity Read ↗

Association between apurinic/apyrimidinic endonuclease 1 rs1760944 T>G polymorphism and susceptibility of cancer: a meta-analysis involving 21764 subjects.Semantic proximity Read ↗

Nuclear expression of human apurinic/apyrimidinic endonuclease (HAP1/Ref-1) in head-and-neck cancer is associated with resistance to chemoradiotherapy and poor outcomeSemantic proximity Read ↗

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinomaSemantic proximity Read ↗

Apurinic/apyrimidinic nuclease 1 drives genomic evolution contributing to chemoresistance and tumorigenesis in solid tumorSemantic proximity Read ↗

APE1 and XRCC1 Protein Expression Levels Predict Cancer-Specific Survival Following Radical Radiotherapy in Bladder CancerSemantic proximity Read ↗

A genetic variation in APE1 is associated with gastric cancer survival in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.