Article

Somatically mutated genes in fatty liver disease have minimal influence on germline risk

2021-10-19

Abstract excerpt

<h4>Background</h4> Understanding the genetics of liver disease has the potential to facilitate clinical risk stratification. We recently identified six genes and one lncRNA enriched for acquired somatic mutations in patients with NAFLD and alcohol-related liver disease. We hypothesised that germline variation in these genes would be associated with risk of liver disease development and contribute to prognosticati...

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Literature Corpus work: e0f31259-06bc-5edf-a6ad-a9404447d0c7
DOI: 10.1101/2021.10.18.21265159

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