Article

Exploring associations between estrogen and gene candidates identified by coronary artery disease genome-wide association studies

2024-08-30

Abstract excerpt

<h4>Introduction</h4> Coronary artery disease (CAD) is the leading cause of death around the world, with well-described epidemiological sex and gender differences in prevalence, pathophysiology and management outcomes. It has been hypothesized that sex steroids, like estrogen, may contribute to these sex differences. There is a relatively large genetic component to developing CAD, with heritability estimates rangi...

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Literature Corpus work: e0ed745c-4169-5bff-88d3-80ddc8694bcd
DOI: 10.1101/2024.08.29.24312812

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