Article
Premature coronary artery disease in women: sex-specific risk factors, pathogenetic mechanisms and clinical implications.
Annals of medicine - 1 Dec 2026
Li Fei, Hong Dan, Yang Mei, Pang Zhilin, Xi Haolin, Zhang Qingyuan, Li Chuanchang, Mo Long, Peng Liming
Abstract excerpt
INTRODUCTION: Premature coronary artery disease (PCAD) in women, defined as onset ≤65 years, accounts for 20-30% of CAD cases. The clinical implications, pathogenic processes, and sex-specific risk factors of female PCAD are summarized in this review. DISCUSSION: Women have unique patterns in the traditional metabolic risk factors of smoking, diabetes, obesity, and hypertension. Elevated triglyceride-rich...
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