Article

IgSeqR: a protocol for the identification, assembly, and characterization of full-length tumor Immunoglobulin transcripts from unselected RNA sequencing data

2024-09-04

Abstract excerpt

Immunoglobulin (IG) gene analysis provides fundamental insight into B-cell receptor structure and function. In B-cell tumors, it can inform the cell of origin and clinical outcomes. Its clinical value has been established in the two types of chronic lymphocytic leukemia with unmutated or mutated IGHV genes and is emerging in other B-cell tumors. The traditional PCR-based techniques, which are labor-intensive, rel...

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Literature Corpus work: e0dfd025-1992-5df7-b10a-4394a3e574c9
DOI: 10.1101/2024.09.03.611002

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