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The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

17 Aug 2017

Abstract excerpt

BACKGROUND: RNA sequencing (RNA-seq) has become an indispensable tool to identify disease associated transcriptional profiles and determine the molecular underpinnings of diseases. However, the broad adaptation of the methodology into the clinic is still hampered by inconsistent results from different RNA-seq protocols and involves further evaluation of its analytical reliability using patient samples. Here, we...

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PMID: 28818039
DOI: 10.1186/s12864-017-4039-1

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