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An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer

22 Sept 2013

Abstract excerpt

BACKGROUND: Pancreatic cancer is a highly lethal cancer with limited diagnostic and therapeutic modalities. METHODS: To begin to explore the genomic landscape of pancreatic cancer, we used massively parallel sequencing to catalog and compare transcribed regions and potential regulatory elements in two human cell lines derived from normal and cancerous pancreas. RESULTS: By RNA-sequencing, we identified 2,146...

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PMID: 24053169
DOI: 10.1186/1755-8794-6-33

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